Poor early detection major factor poorer CRC outcomes among African American men

African American men have the lowest five-year survival rate for colorectal cancer (CRC) and low adherence to recommended early detection screening (colonoscopy and home-based stool testing kits) is a major contributing factor, according to the findings of a study, ‘Interventions for increasing colorectal cancer screening uptake among African-American men: A systematic review and meta-analysis’, published the journal PLOS ONE.

First colorectal endoscopic submucosal dissection using flexible endoscopic robotic system

The Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) has been collaborating with researchers from Singapore since 2010 to develop a flexible endoscopic robotic system. This novel system was specifically designed to enhance the safety and efficacy of endoscopic submucosal dissection (ESD) for the treatment of gastrointestinal cancer. Using the first prototype flexible endoscopic robot, the team at CU Medicine successfully performed ESD for treatment of early gastric cancer in 2011.

Molecular mechanism behind one of the causes of colorectal cancer

A team of scientists has unravelled the molecular mechanism behind one of the causes of colorectal cancer and a treatment target. In an extensive series of experiments, a team of scientists, including Tadasuke Tsukiyama from the Faculty of Medicine at Hokkaido University, has described a molecular mechanism by which mutations at one site in RNF43 cause cancer and have also described a potential method to treat these cancers.

High-risk colorectal cancer patients lack knowledge about colonoscopy

Patients with advanced colorectal polyps are a major risk factor have a three-fold higher risk of developing colorectal cancer and therefor a three-year follow up interval of colonoscopy is generally recommended. Many clinicians rely on self-reports from their high-risk patients about their need and proper interval for repeat surveillance colonoscopy.