RECOVER trial to examine effect of low- vs normal-pressure pneumoperitoneum during laparoscopic colorectal surgery

Researchers from the Netherland have begun a clinical trial to investigate the effect of lower insufflation pressures facilitated by deep neuromuscular blockade (DNB) on patient outcomes after laparoscopic colorectal procedures. Specifically, the study will identify whether low pressure pneumoperitoneum (PNP) and DNB enhances recovery after colorectal laparoscopic surgery and whether this could be a valuable addition to the Enhanced Recovery After Surgery (ERAS) guidelines.

Medicaid expansion has led to earlier cancer detection among individuals with low income

The likelihood of being diagnosed with advanced cancer decreased among individuals with low income after expansion of Medicaid coverage, according to researchers from the Case Western Reserve University School of Medicine's Center for Community Health Integration in Cleveland, OH.

Hypertension medications could reduce colorectal cancer risk

Medications commonly prescribed to treat hypertension may also reduce patients' colorectal cancer risk, according to researchers from University of Hong Kong in Hong Kong, China, Based on the findings of this large study, taking these medications may also reduce colorectal cancer risk, the third most common cancer and is the second leading cause of cancer death worldwide.

Novel method for multiparametric-MRI rectal cancer diagnosis

An intelligent recognition method has been developed and firstly applied to achieve automatic lymph node (LN) detection and segmentation (auto-LNDS) of rectal cancer patients before surgery. This development was achieved by Gao Xin's research team from the Suzhou Institute of Biomedical Engineering and Technology of the Chinese Academy of Sciences (SIBET, CAS), in collaboration with MENG Xiaochun from Sixth Affiliated Hospital of Sun Yat Sen University, and other three 3A hospitals spread across different regions in China.

Rapid genomic CRC testing improves therapy selection for patients

A multi-centre study comparing a new cartridge-based laboratory testing device called the Idylla automated system (Biocartis) to current standard-of-care testing methods, has reported that average turnaround time for test results could be cut by more than 65% from 15 days to five days, with some results available in a single day.

Patient aged 57 and older at increased risk from 30-day post-colonoscopy complications

Patients aged 75 years and older appeared to have a higher risk of post-colonoscopy complications during the 30-day period after colonoscopy compared with screen-eligible patients and the decision to perform colonoscopy should be considered carefully in older patients, particularly in the presence of comorbidities, according to researchers from University of Toronto, Toronto and McMaster University, Hamilton, Ontario, Canada.

Colorectal cancer hotspots in the US

A study by researcher at the University of Utah has found many new diagnoses of colorectal cancer are occurring in counties in the lower Mississippi Delta, west-central Appalachia and eastern Virginia/North Carolina. These ‘hotspot’ areas - where colorectal cancer is on the rise and actually killing young men at high rates - revealed several trends about who these men are and how their cancer progresses.

New way of identifying tumour response to immunotherapy

Scientists at City of Hope, working in collaboration with researchers at Translational Genomics Research Institute (TGen) and other colleagues across the US, have found that the actions of circulating immune cells - namely how they differentiate and signal - at the start of immunotherapy treatment for cancer can inform how a patient will respond to the therapy.