People with MS may not be at higher risk of colorectal cancers

People with multiple sclerosis (MS) may not be at higher risk of developing two of the three cancers that occur most commonly in people with MS, breast and colorectal cancer, than people who do not have the disease, according to a study published in Neurology, the medical journal of the American Academy of Neurology. However, the study did find that people with MS had a higher incidence of bladder cancer.

Vitamin D regulates calcium in distal segments of the intestine

Researchers at Rutgers New Jersey Medical School have reported Vitamin D regulates calcium in a section of the intestine that previously was thought not to have played a key role. The findings have important implications on how bowel disease, including ulcerative colitis and Crohn's disease, may disrupt calcium regulation.

Therapeutic PD-1 cancer vaccine shown to be safe and effective in CRC animal study

A study led by researchers at The Ohio State University (OSU) Comprehensive Cancer Center, Arthur G James Cancer Hospital and Richard J Solove Research Institute (OSUCCC—James) have described a potential therapeutic anticancer vaccine that frees suppressed cancer-killing immune cells, enabling them to attack and destroy a tumour.

Researchers identify specific gut bacteria linked to IBS

Researchers at the University of Gothenburg have detected a connection between Brachyspira, a genus of bacteria in the intestines, and irritable bowel syndrome (IBS) especially the form that causes diarrhoea. Although the discovery needs confirmation in larger studies, there is hope that it might lead to new remedies for many people with irritable bowel syndrome.

Gene therapy to target the spread of bowel cancer

For the first time, SAHMRI and University of Adelaide researchers are investigating gene therapy as an option to help people with metastatic bowel cancer. Like most cancers, bowel cancer is surrounded by many normal cells that are corrupted to support cancer growth. Dr. Susan Woods, A/Prof Daniel Worthley and their team have been studying why some of these supportive cells (fibroblasts) assist cancer growth, while others actively work to stop it.

Location impacts CRC mortality rates among young women in US

Women diagnosed with early-onset colorectal cancer have a greater risk of dying from the disease depending upon their county of residence in the US, according to a study, ‘Community Health Behaviors and Geographic Variation in Early-Onset Colorectal Cancer Survival Among Women’, published in Clinical and Translational Gastroenterology.