Aspirin to prevent colon cancer underutilised in high-risk patients

Researchers from Florida Atlantic University's Schmidt College of Medicine have reported that aspirin is underutilised to prevent colorectal cancer as well as recurrent polyps in high risk patients. Their study, ‘Underutilization of aspirin in patients with advanced colorectal polyps,’ was published in The American Journal of Medicine

Team developing VR technology for training and assessment of colorectal surgeons

Colorectal surgery is a hands-on activity, but in recent years the effectiveness of traditional assessment methods in evaluating surgeons' technical skills has been called into question. A team of collaborators with ties to Rensselaer Polytechnic Institute, New York, is pioneering the use of virtual reality (VR) technologies to train and objectively evaluate colorectal surgeons without putting any patients at risk. The project is supported by the National Institute of Biomedical Imaging and Bioengineering.

Cannabinoid compounds may inhibit growth of colon cancer cells

Penn State College of Medicine researchers have reported that some cannabinoid compounds may actually inhibit the growth of colon cancer cells in the laboratory. The researchers tested the effects of synthetic cannabinoid compounds on colon cancer cells in an experiment in test tubes. While the compounds most commonly associated with cannabis - THC and CBD - showed little to no effect, ten other compounds were effective at inhibiting cancer cell growth.

Sitting whilst watching TV linked to colorectal cancer risk before age 50

A new study, ‘Sedentary Behaviours, TV Viewing Time, and Risk of Young-Onset Colorectal Cancer,’ published in JNCI Cancer Spectrum, has identified a connection between prolonged time spent sitting while watching TV and increased risk of colorectal cancer for younger Americans. These findings are among the first to link specific sedentary behavioural patterns with risk of young-onset colorectal cancer.

Stereotactic radiation improves long-term survival in patients with stage-IV cancers

The first report from a phase II, multi-centre clinical trial indicates that a newer, more aggressive form of radiation therapy - stereotactic radiation - can extend long-term survival for some patients with stage-IV cancers while maintaining their quality of life. The study, ‘Initial Results of a Multicenter Phase 2 Trial of Stereotactic Ablative Radiation Therapy for Oligometastatic Cancer,’ was published in the International Journal of Radiation Oncology, Biology, Physics, the scientific journal of the American Society for Radiation Oncology (ASTRO).

US study comparing options for treating faecal incontinence

A US$18.8 million, five-year study funded by the National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases is assessing three treatment options: medical management, pacemaker to stimulate the sacral nerve and biofeedback. Faecal incontinence, or accidental stool leakage, affects some 8 to 10 percent of the 325 million people in the United States. In up to half of patients, there is both faecal and urinary incontinence.

Bowel cancer increasing among younger Australians, but decreasing in older population

Researchers from the University of New South Wales have reported that the incidence of bowel cancer, which includes colon and rectal cancer, has increased by up to 9 percent in people under 50 from the 1990s until now. The study, ‘Exposure to Trace Elements and Risk of Skin Cancer: A Systematic Review of Epidemiologic Studies,’ published recently in Cancer Epidemiology, Biomarkers and Prevention also found bowel cancer incidence is falling in older Australians.

The association between colitis and colon cancer

Researchers from the Medical College of Georgia at Augusta University have discovered how chronic inflammation of the colon enables cancer. A scientific team led by Dr Kebin Liu has found it turns one more protective mechanism against us and silences another. The research is featured in the paper, ‘Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis,’ published in Cell Reports.