Tailored lifestyle feedback during colorectal cancer screening improved health behaviours

A programme that provided individually tailored lifestyle recommendations for patients undergoing screening for colorectal cancer helped encourage healthy behaviour, according to results of a study’ Improving Cancer Preventive Behaviors: A Randomized Trial of Tailored Lifestyle Feedback in Colorectal Cancer Screening,’ published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

Antibiotic prophylaxis regimens less effective at preventing SSIs following colorectal surgery

Antibiotic prophylaxis regimens are becoming less effective at preventing surgical site infections following colorectal surgery, according to researchers at the Center for Disease Dynamics, Economics & Policy and Princeton University determined through a systematic review of available literature.

microRNAs are predictors of Crohn's disease progression

A new study conducted in adult and paediatric patients with Crohn's disease, led by UNC School of Medicine researchers and published in the Journal of Clinical Investigation Insight, has found that a set of biomolecules known as microRNAs, specifically microRNA-31 (miR-31), can help predict which patients with Crohn's disease are at higher risk for the development of severe problems that may require surgical removal of the large intestine.

AGA issues medical management of opioid-induced constipation guidelines

Traditional laxatives are recommended as first-line agents to treat patients with a confirmed diagnosis of opioid-induced constipation (OIC), according to a new guidelines, ‘American Gastroenterological Association Institute Guideline on the Medical Management of Opioid-Induced Constipation,’ published in the journal Gastroenterology, from the American Gastroenterological Association (AGA).

Bowel Cancer UK campaigns to end bowel cancer capacity crisis

Bowel Cancer UK has handed in an open letter to the to the UK government calling for a fully funded action plan to tackle NHS staff shortages in diagnostic services for bowel cancer – England’s second biggest cancer killer. The letter comes ahead of the Government spending review and calls on the Chancellor and Health Secretary to invest in more NHS staff to cope with the rising demand for bowel cancer tests.

Inflammatory proteins in the colon increase incrementally with weight

A new study shows that two inflammatory proteins in the colon increase in parallel with increasing weight in humans. An incremental rise in these pro-inflammatory proteins (called cytokines) was observed along the entire spectrum of subjects' weights, which extended from lean to obese individuals. In participants with obesity, there was evidence that two pre-cancerous cellular pathways known to be triggered by these cytokines were also activated.

ESCP studies to assess surgical techniques and post-operative outcomes for patients

European Society for Coloproctology (ESCP) has announced it is establishing additional cohort studies on robotic colorectal surgery, the management of acute severe Ulcerative Colitis and parastomal hernia repair in 2019. The ESCP has previously undertaken a major international audit of colorectal operations to understand which are most widely used techniques across the world, which appear to be associated with the best outcomes and where further research needs to be undertaken.