microRNAs are predictors of Crohn's disease progression

A new study conducted in adult and paediatric patients with Crohn's disease, led by UNC School of Medicine researchers and published in the Journal of Clinical Investigation Insight, has found that a set of biomolecules known as microRNAs, specifically microRNA-31 (miR-31), can help predict which patients with Crohn's disease are at higher risk for the development of severe problems that may require surgical removal of the large intestine.

Bowel Cancer UK campaigns to end bowel cancer capacity crisis

Bowel Cancer UK has handed in an open letter to the to the UK government calling for a fully funded action plan to tackle NHS staff shortages in diagnostic services for bowel cancer – England’s second biggest cancer killer. The letter comes ahead of the Government spending review and calls on the Chancellor and Health Secretary to invest in more NHS staff to cope with the rising demand for bowel cancer tests.

Inflammatory proteins in the colon increase incrementally with weight

A new study shows that two inflammatory proteins in the colon increase in parallel with increasing weight in humans. An incremental rise in these pro-inflammatory proteins (called cytokines) was observed along the entire spectrum of subjects' weights, which extended from lean to obese individuals. In participants with obesity, there was evidence that two pre-cancerous cellular pathways known to be triggered by these cytokines were also activated.