Low risk of rectal cancer after colectomy in UC patients

The risk for rectal cancer after colectomy in patients with ulcerative colitis (UC) is low, in relative and absolute terms, after reconstruction with an ileal pouch–anal anastomosis (IPAA). However, compared with the general population, an ileorectal anastomosis (IRA) and diverted rectum are associated with an increased risk of rectal cancer, but the absolute risk is low. These are the conclusions from a paper from a Swedish national cohort study that included more than 5,800 patients.