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Owen Haskins, Managing Editor, Coloproctology News

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Colon cancer cell switch helps evades treatment

Researchers in Germany have discovered that colon cancers are often resistant to existing drug treatments because they are composed of two different cell types that can replace each other when one cell type is killed. The study, 'Targeting tumor cell plasticity by combined inhibition of NOTCH and MAPK signaling in colon cancer', published in the Journal of Experimental Medicine, suggests that combination therapies targeting both cell types at once may be more effective at treating colorectal cancer, the third highest cause of cancer-related death in the United States.

15th International Colorectal Meeting: Rectal cancer - pushing the limits of watch and wait

In a series of interviews, we will be previewing this year’s 15th International Colorectal Meeting in Turin, 16-18 April. We talked to Dr Rodrigo Oliva Perez from the Instituto Angelita & Joaquim Gama and the Ludwig Institute for Cancer Research, São Paulo, Brazil, about the ‘watch and wait’ approach for treating rectal cancer.

15th International Colorectal Meeting: Colorectal Endoscopic submucosal dissection

In a series of interviews, we will be previewing this year’s 15th International Colorectal Meeting in Turin, 16-18 April. We talked to Professor Adam Dziki from Medical University, Lodz, Poland, about the benefits of colorectal endoscopic submucosal dissection (CR-ESD) some of the procedures’ key technical and anatomical concerns and some of the topics will be discussing during his presentation at the meeting.

15th International Colorectal Meeting: Continent ileostomy

In a series of interviews, we will be previewing this year’s 15th International Colorectal Meeting in Turin, 16-18 April. We talked to Professor Tom Oresland from Akershus University Hospital, Norway, about the benefits of continent ileostomy (Kock pouch) and some of the key topics he will be discussing during his presentation at the meeting.

15th International Colorectal Meeting - an interview with Dr Mario Trompetto

In a series of interviews, we will be previewing this year’s 15th International Colorectal Meeting in Turin, 16-18 April. We talked to Dr Mario Trompetto, Head of the Department of Colorectal Surgery at the S Rita Clinic in Vercelli (Italy), member of the meeting’s Scientific Secretariat, who highlighted some of the key sessions, presentations and speakers, as well as encouraging those with an interest in coloproctology to attend the meeting.

ACPGBI publishes paper outlining future training needs for the colorectal community

After consultation with its members, the Association of Coloproctology of Great Britain and Ireland (ACPGBI) has published a paper outlining the perceived educational needs, knowledge and skill gaps, and current barriers of the UK and Ireland colorectal community. The paper, ‘Developing a national colorectal educational agenda: a survey of the Association of Coloproctology of Great Britain and Ireland’, was published in Colorectal Disease.

Nitrate in drinking water increases the risk of colorectal cancer

There is an increased risk of colon and rectal cancer in connection with nitrate in drinking water, according to a study from Aarhus University, Aarhus and the Geological Survey of Denmark and Greenland (GEUS) and the National Centre for Register-based Research also from Aarhus University Denmark. Nitrate in groundwater and drinking water, which primarily comes from fertilisers used in the agricultural production, has not only been subject to decades of environmental awareness - it has also been suspected of increasing the risk of cancer.