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England faces backlog of half-million endoscopies and rising

Wed, 03/24/2021 - 15:09
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A backlog of nearly half a million endoscopy procedures, essential for diagnosing gastrointestinal cancers and diseases, has built up during the COVID-19 pandemic, according to an analysis of NHS England data led by University College London researchers. The outcomes were featured in the paper, ‘Predicting endoscopic activity recovery in England after COVID-19: a national analysis’, published in The Lancet Gastroenterology & Hepatology, show the number of endoscopies being performed in April 2020, the month following the first lockdown, fell by over 90%. By January 2021 researchers estimated the backlog was 476,000, and this figure could potentially rise to more than 870,000, should there be a further full or partial lockdown and/or a slow return to normality.

Clinicians are now calling on the UK government and NHS to implement a concerted mitigation plan, in order to prioritise patients in urgent need of an endoscopy and help reduce the health impact and consequences.

"The COVID-19 pandemic has had a significant impact on NHS diagnostic services. This has included endoscopic services which are crucial in the diagnosis of gastrointestinal cancers and diseases, such as bowel, stomach and oesophageal cancer,” explained the study’s lead author, Dr Alex Ho from UCL’s Division of Surgery and Interventional Science. “In this study, we sought to quantify the national backlog of endoscopic procedures in England and assess how interventions may affect this backlog."

For the study, researchers analysed the number of endoscopies (colonoscopies, flexible sigmoidoscopies and gastroscopies) performed across England, using NHS England's Monthly Diagnostic Waiting Times and Activity dataset. To estimate the potential backlog they compared the number of endoscopies performed by month from January 1 2018 to October 31 2020, from 125 NHS trusts in England.

In April 2020, the month following lockdown, 10,476 endoscopy procedures were performed, representing a 90.5% drop compared with April 2019, when 110 584 procedures were done. Endoscopy procedures recovered to 105,716 in October 2020, 84.5% of the 125,072 done in October 2019.

As part of a modelling analysis, researchers concluded that even if endoscopy procedures reached 100% of pre-pandemic monthly totals from November 2020, the backlog in January 2021 would be 476,000.

Modelling against further interruption (i.e full or partial lockdown), researchers found a further two-month interruption would add an extra 15.4% or 73,000 to the backlog total, a four-month interruption would add an extra 43.8% or 208,000, and a six-month interruption (worst case scenario) would add an extra 82.5% to the potential backlog - equating to 393,000 additional procedures (so a potential backlog of 870,000). However, the researchers explained the vaccine rollout and lessons learnt from the first wave mean the higher figure will likely be reduced.

Assuming no further interruption (recovery phase), researchers modelled the backlog from January 2021 to January 2023, using the average number of procedures carried out in 'normal times' researchers estimated the backlog recovery at 90% of capacity through to 130%. If 90% of procedures took place the backlog by January 2023 would be 811,000. At 100% the backlog would be 476,000. To clear the backlog by January 2023, procedures would need to be conducted at 130%.

In a separate scenario, the researchers asked what would happen if the NHS used the FIT (fecal immunochemical test) to triage/prioritize people for colonoscopies. They found that even with nationwide FIT implementation it would reduce colonoscopy volumes to around 75% of usual levels, with the colonoscopy backlog not cleared until early 2022 at the earliest.

"Our study highlights the scale the COVID-19 pandemic has had on endoscopic services on the NHS in England. Even with mitigation measures, such as FIT triaging, it could take much longer than a year to eliminate the pandemic-related backlog,” added corresponding author, Professor Laurence Lovat also from UCL’s Division of Surgery and Interventional Science. “Urgent action is required by key stakeholders, including individual NHS trusts, Clinical Commissioning Groups, British Society of Gastroenterology, and NHS England, to tackle the backlog and prevent delays to patient management."

The number of extra deaths or serious illness caused by delays in endoscopy procedures and diagnosis, was not covered in this study. However, several modelling studies have been published in this area.

"These data provide yet more evidence of the disastrous impact of COVID on cancer services and ultimately cancer patients. The precipitous drop in endoscopic services nationally (to less than 10% of pre COVID levels) is extremely worrying,” explained co-author, Professor Mark Lawler, Professor of Digital Health, Queen's University Belfast and Scientific Director DATA-CAN, the UK's Health Data Research Hub for Cancer. "We need to address the enormous backlog that has accumulated as a matter of urgency, otherwise we risk significant increases in deaths from colorectal and oesophageal cancer over the next five years. In previous work, we have shown that a six month delay could lead to nearly 3,000 excess deaths in people with cancers of the gastrointestinal tract."

The UCL-led study was carried out in collaboration with researchers at Queen's University Belfast and Newcastle University.

Funded sources included, the Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS) at UCL, National Institute for Health Research University College London Hospitals Biomedical Research Centre, and DATA-CAN.

To access this paper, please click here